My current research is focused on the characterization of functional synaptic adaptations that contribute to the development of anxiety-like behaviors and relapse in a model of alcohol abuse.  I primarily use whole cell patch clamp electrophysiology in conjunction with biochemical and behavioral approaches to gain a broad understanding of how synaptic function is impacted during protracted withdrawal.  My current research characterizes alterations in NMDA receptor function and expression associated with short and long-term withdrawal from chronic ethanol exposure.