Matthew Henry

Matthew Henry
Position(s)
Chair and Associate Professor Physiology and Pharmacology
Associate Professor Master of Science in Biomedical Sciences
Doctor of Osteopathic Medicine
Co-Director of Research
Office Phone 515-271-1434
Fax 515-271-7031
Email matthew.henry@dmu.edu
Education
  • Postdoctoral fellow, University of Iowa, College of Medicine, Department of Internal Medicine, Division of Hematology/Oncology
  • Ph.D., Pharmacology, University of Iowa
  • B.S., Biology, Marquette University

Awards and honors

2011-2013 – American Association of Colleges of Osteopathic Medicine Medical Education Research Mini-Grant Award.

2010-2015 – Fellow of the National Academy of Osteopathic Medical Educators, Scholarship of Teaching & Learning

2008-2011 – Dean’s Award for Research in Education, Des Moines University

2008 – Dean’s Award for Outstanding Community Service, Des Moines University

2007-2008 – Iowa Science Foundation Research Grant (ISF-07-07)

2005-2009 – Academic Research Enhancement Award, National Institutes of Health (Collaborator/Consultant)

2005 – Scientist Educator Award, Des Moines University

2002 – Institutional National Research Service Award Recipient, “Programs in Hematology: Molecular and Cell Biology of Blood Cells”

Biomedical Research Interests

Our lab studies aspects of molecular and cellular pharmacology related to multiple disease processes. Our goals focus on investigating mechanisms of cellular communication and cellular proliferation.  Studies have included aspects of blood cell proliferation, cancer cell proliferation, bacterial cell proliferation, endothelial cell proliferation, vascular smooth muscle cell proliferation, and cardiomyocyte communication.

Medical Education Research

Undergraduate medical education is continually changing to meet the demands and needs of our future health care practitioners. We are interested in developing and assessing methods of disseminating medical knowledge in order to identify the best practices for educating our future health care providers. Currently we are investigating the impact of using medical simulators on student learning in both the didactic and clinical components of medical training.

Publications

Moffit, JA, MK Henry, KC Welliver, AJ Jepson, and ER Garnett. Hindlimb unloading results in increased predisposition to cardia arrhythmias and alters left ventricular connexin43 expression. Am J Physiol Regul Integr Comp Physiol 304: R362-R373, 2013

Wilson, WA, MK Henry G Ewing, J Rehmann, CA Canby, JT Gray and EP Finnerty. A pre-matriculation intervention to improve the adjustment of students to medical school. Teaching & Learning in Medicine; 23(3): 256-262., 2011

Hamadmad S, Henry MK, and Hohl RJ. Erythropoietin receptor signal transduction requires protein geranylgeranylation. J Pharmacol Exp Ther; 316(1):403-409., 2006

Chakravarti P., Henry MK, Quelle FQ. Prolactin and heregulin override DNA damage-induced growth arrest and promote phosphatidylinositol-3 kinase-dependent proliferation in breast cancer cells. Int J Oncol; 26: 509-514., 2005

Henry MK, Nimbalkar D, Hohl RJ, and Quelle FW. Cytokine induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells. Exp Cell Res; 299: 257-266, 2004

Nimbalkar D, Henry MK, and Quelle FW. Cytokine activation of phosphoinositide 3-kinase sensitizes hematopoietic cells to cisplatin-induced death. Cancer Res; 63: 1034-1039. , 2003

Eapen AK, Henry MK, Quelle DE, and Quelle FW. DNA damage-induced G1 arrest in hematopoietic cells is overridden following PI-3 kinase dependent activation of cdk2. Mol Cell Biol; 21: 6113-6121. , 2001

Henry MK, Lynch JT, and Quelle FW. DNA damage-induced cell cycle arrest of hematopoietic cells is overridden by activation of the PI-3Kinase/Akt signaling pathway. Blood; 98: 834-841., 2001

Henry MK, Unsworth BR, Sychev V, Guryeva TS, Dadasheva OA, Piert SJ, Lagel KE, Dubrovin LC, Jahns GC, Boda K, Sabo V, Samet MM, and Lelkes PI. Investigator: Lelkes PI. Launch conditions might affect the formation of blood vessels in the quail chorioallantoic membrane. Folia Vet; 42 Suppl: S25-31. , 1998