Sympathetic Mechanisms of Thermoregulatory Reflex Cutaneous Vasoconstriction
- Describe how skin blood flow is controlled and how this can serve as a model for microvascular function.
- Explain how the cutaneous vasoconstriction response is altered with primary aging.
- Identify future experimental directions designed to further elucidate how the cutaneous microvasculature respond to thermal stress.
Dr. James Lang’s mentorship throughout his academic path has been from investigators that specialized in thermoregulation and fluid homeostasis; not only as it relates to exercise performance, but how these mechanisms are altered with various disease states. During this time, he has developed a more specific interest in sympathetic mechanisms in skin and how these pathways may serve as a model for understanding how the microvasculature responds to stress. During his postdoctoral training, Dr. James Lang studied muscle sympathetic nerve activity as it relates to blood pressure control mechanisms in humans.
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